The current version of HKL-3000 distributed by HKL Research is version 712.

For the Rigaku detectors (Raxis-IV++, Raxis-HTC, Pilatus3 R 200K, and others) HKL-3000 is available as a bundled software and distributed as HKL-3000R. HKL-3000R users should contact Rigaku directly for information about the latest version. 

HKL-3000 users who have obtained their license directly from HKL Research can download the installer for the latest version from our ftp server ( The password can be obtained from You may also use a graphical ftp application, or use the command "ftp" from a terminal window (to open a terminal window in MAC OS X, open the Finder's Go menu, choose Applications, then choose Utilities and select Terminal). Ftp should use the passive option:

ftp -p

HKL-3000 interacts with many widely used programs like CCP4, SOLVE, RESOLVE, MLPHARE, SHELXD and SHELXE, ARP/wARP, DM, MOLREP, REFMAC, and MolProbity. These programs must be obtained directly from their respective authors or distributors.


CCP4: Collaborative Computational Project,Number 4 (1994). Acta Cryst. D50, 760-763

SOLVE: Terwilliger, T. C. & Berendzen, J. (1999). Acta Cryst. D55, 849-861.

RESOLVE: Terwilliger, T. C. (2004).J. Synchrotron Rad. 11, 49-52.

MLPHARE: Otwinowski, Z. (1991). Proceedings of the CCP4 Study Weekend. Isomorphous Replacement and Anomalous Scattering, edited by W. Wolf, P. R. Evans & A. G. W. Leslie, pp. 80-86. Warrington: Daresbury Laboratory.

SHELXD: Schneider, T. R. & Scheldrick, G.M. (2002). Acta Cryst. D58, 1772-1779.

SHELXE: Scheldrick, G. M. (2002). Z. Kristallogr. 217, 644-650.

ARP/wARP: Perrakis, A., Morris, R. & Lamzin, V. S. (1999). Nature Struct. Biol. 6, 458-463.

DM: Cowtan, K. (2001). Acta Cryst. D57, 1435-1444. Cowtan, K. & Main, P. (1998). Acta Cryst. D54, 487-493. Cowtan, K. D. & Zhang, K. Y. (1999). Prog. Biophys. Mol. Biol. 72, 245-270.

MOLREP: Vagin, A. A. & Teplyakov, A. (1997). J. Appl. Cryst. 30, 1022-1025. Vaguine, A. A., Richelle, J., Wodak, S. J. (1999). Acta Cryst. D55, 191-205.

REFMAC: Murshudov, G. N., Vagin, A. A. & D odson, E. J. (1997). Acta Cryst. D53, 240-255.

MolProbity: Vincent B. Chen, W. Bryan Arendall III, Jeffrey J. Headd, Daniel A. Keedy, Robert M. Immormino, Gary J. Kapral, Laura W. Murray, Jane S. Richardson and David C. Richardson (2010) MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallographica D66: 12-21. Ian W. Davis, Andrew Leaver-Fay, Vincent B. Chen, Jeremy N. Block, Gary J. Kapral, Xueyi Wang, Laura W. Murray, W. Bryan Arendall III, Jack Snoeyink, Jane S. Richardson and David C. Richardson (2007) MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Research 35: Web Server issue, W375-W383.